Week 1 NFL Live Odds Lines Spreads Wagerline



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Week 1 NFL Live Odds Lines Spreads



On Thursday, September 8, the Los Angeles Rams welcome the Buffalo Bills for the opening game of the 2022 NFL regular season, kicking off their Super Bowl defence in earnest. At the time of press, Los Angeles was awarded 2.5 points, and the total was set at 52. NBC will air the game at 8:20 PM ET.

The Rams debuted at -1 back in mid-May, but Buffalo has garnered much of the attention this summer. They begin the 2017 season as +550 favourites to win Super Bowl LVII. The Bills do have one significant issue for Week 1: after dismissing rookie punter Matt Araiza last Saturday, they need to hire a punter. During Buffalo's final preseason game, backup quarterback Matt Barkley took over.

Despite having most of their key players from 2021 back, the reigning champs are seventh on the Super Bowl betting list at +1200. QB Matthew Stafford, who experienced elbow pain last year and was given a very light effort during training camp, is causing some anxiety. After tearing his ACL during their triumph over the Cincinnati Bengals in Super Bowl LVI, WR Odell Beckham Jr. is still unsigned and has months to wait before making a comeback.

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